French Bulldog DNA

Frenchies are one-of-a-kind dogs that inherit a genetic pattern that make them distinct from other dogs, especially bulldogs. In this article, we will learn more about French Bulldog DNAs, their genetic health testing, and how to interpret DNA results (of their colors), including common and very rare genetic health risk factors. It is important to know how to do these things in order to get the healthiest bulldog that you could ever have for a long period of its lifetime.

Genetic Health Testing for French Bulldogs

French Bulldog DNA

Frenchies have a special genetic health testing method called a 4-panel health test. What is it?

A 4-panel health test for French Bulldogs looks for four of the breed’s most prevalent health issues. These diseases include congenital deafness, von Willebrand disease, hip dysplasia, and elbow dysplasia. A little sample of your dog’s blood must be drawn for the test, which is often carried out by a veterinarian.

There are two primary reasons why you might want to think about getting your French Bulldog a 4-panel health test. 

  • The first benefit is that it can assist you in determining whether your dog is at risk for any of these ailments. If your dog does experience one of these ailments, you can utilize this knowledge to ensure that they receive the best care and treatment available. 
  • The second reason is that before they would sell you a puppy, many breeders will insist that you undergo this exam. This is done in order to guarantee that the puppies they are selling are as healthy as possible and won’t grow up with any of these diseases.

How to Interpret DNA Results for French Bulldogs

French Bulldog DNA

(Note: DNA results interpretation only applies to color and not health. Contact a veterinarian or animal hospital about genetic DNA tests and let the experts interpret them.)

If you are not aware of the several genes that produce uncommon colors, the many different reporting formats that French Bulldog DNA testing businesses offer might be quite challenging to read. Here are some examples of common alleles and explanations of what they mean.

Every attribute that has been discussed consists of two pairings, one of which is passed on from each parent. Some traits or colors require two copies (recessive genes), whereas others can be seen with just one (dominant genes).

  • A-Locus (Pattern)

The three possibilities (alleles) for the A-locus are Ay – Fawn, At – Tan, and a – solid.

Your DNA result may include both genes (At/Ay) or just the copies of each gene separately ( At one copy tan, Ay 1 copy fawn. a – 1 copy solid).

French Bulldog DNA

  • Brown/Testable Chocolate B-Locus

This gene produces Isabella French Bulldogs by combining with other genes to produce brown, also referred to as testable chocolate. It will appear as b/b or state the B-locus has two copies. 1 copy would be a carrier.

B/B or N/N (no copies) – negative

B/b or b/N  (1 copy) – carries but does not display testable chocolate.

b/b  (2 copies) displays testable chocolate

  • Cocoa

The primary chocolate gene creates a different shade of brown compared to the B-Locus. Likewise, when combined with other visible colors will look different too.

Common Genetic Health Risk Factors

French Bulldog DNA

Here are two of the most common genetic health risk factors for French Bulldogs:

Patella Luxation

Frenchies have an inherent tendency to luxating patella, like many tiny dog breeds. This happens when the patella, or knee cap, slips out of its groove at the front of the stifle (knee) joint.

Hip Dysplasia

Another genetic problem that Frenchies are vulnerable to is hip dysplasia, which prevents the ball and socket hip joint from developing normally. As a result, the hip joint degenerates because it no longer slides smoothly but instead rubs and grinds. Hip dysplasia advances as a result of environmental variables like obesity, as well as excessive growth and exercise.

Very Rare Genetic Health Risk Factors

French Bulldog DNA

Here are the very rare genetic health risk factors for Frenchies:

Chondrodystrophy (CDDY and IVDD) and Chondrodysplasia (CDPA)

Many dog breeds have the short-legged trait known as chondrodysplasia. Short legs, premature disc degeneration, and an elevated risk of disc herniation are all features of the distinct mutation known as chondrodystrophy.

Canine Multifocal Retinopathy 1 (CMR1)

An inherited eye condition called canine multifocal retinopathy is characterized by patches of a detached retina. Usually, the condition does not result in blindness or impaired eyesight.

French Bulldog DNA

Degenerative Myelopathy (DM)

An inherited neurological condition in dogs called degenerative myelopathy (DM) is characterized by gradual muscle atrophy and lack of coordination, usually starting in the hind limbs.

Hyperuricosuria (HUU)

A genetic condition known as hyperuricosuria causes abnormally high levels of uric acid in the urine, which can result in the development of kidney or bladder stones.

Juvenile Hereditary Cataract (JHC)

An inherited kind of cataract known as juvenile hereditary cataracts clouds the lens of the eye in both symmetrically affected eyes, leading to blindness in dogs in many cases.


French Bulldog DNA

French Bulldogs are one of man’s best choices in getting a breed of dog. They can live up to 10-12 years, with 18 years being the longest. It is important to make use of the benefit of these dogs, and you can do that by knowing their DNA and trying to examine if they would have risks in their lifetime. But whether they live long or short or live with a health condition, it would still be amazing to take care of one.


What are the most common French Bulldog health issues?

Allergies, stenotic nares, cherry eye, and joint issues like hip dysplasia and patellar luxation are the most typical health issues in French Bulldogs.

Are White French Bulldogs deaf?

Compared to French Bulldogs of other colors, white French Bulldogs have a significantly higher risk of developing hearing loss.

What is the most common French Bulldog health issue?

Brachycephalic Airway Syndrome (BAS) is the most typical health condition for these cute pups.

French Bulldog DNA